Injuries such as cuts, bruises, punctures and
lacerations are common perils that every human being undergoes. These
injuries occur due to unforeseen accidents. Road accidents, sport
injuries, military accidents, gunshot wounds, home or workplace
accidents, falls, cuts by a sharp object and bruises can result in
bleeding, which if not properly controlled, can become severe.
Uncontrolled breeding is the second leading cause of
trauma related deaths among civilians. It is also the leading cause of
death among active military personnel. Severe bleeding mainly occurs
when the person has been subjected to a traumatic injury that ruptures
the veins and/or arteries; during surgical procedures; with individuals
with coagulopathy or bleeding disorder that prevent blood from
clotting.
Uncontrolled bleeding causes double vision,
drowsiness, seizures, headaches, convulsions and damage to joints. It
can also result in life threatening brain & organ damage and
eventual death if not stopped in time.
It is imperative to save lives by controlling severe
hemorrhage. Normally, the body’s platelets initiate the blood clotting
process, which changes liquid blood into a clot, eventually stopping
the blood flow. The clotting process activates platelets, followed by
adhesion, aggregation and the development of fibrin from fibrinogen.
When the wound is large or arteries are ruptured,
the platelet action may not be adequate to stop the bleeding in time.
The most conventional method is to dress the wound. The dressing
applies pressure on the wound resulting to cessation of blood flow.
However, conventional dressing and bandages take longer to stop bleeding
and blood may percolate through several layers of dressing.
New & advanced dressing techniques such as
Axiostat®, powered by ‘Axio Clotting Technology (A.C.T)’ comprises of a
biopolymer that initiates the clotting process and stops the bleeding
within few minutes after application.
Haemostatic wound dressing refers to the process of
applying specially designed materials to stop blood loss by
accelerating the blood clotting process. The material is applied
directly on the bleeding site and stops bleeding shortly after
application.
Wound dressing in emergency conditions requires a
fast and effective application process. This ensures that bleeding
ceases as quickly as possible. Cases of accidents, injuries, gunshot
wounds where there is profuse bleeding require materials such as
Haemostatic dressings. These materials are tailor-made to accelerate
blood clotting. They are also sterile and prevent infections.
Specially designed materials can be applied in
different parts of the body such as limbs, torso, head, neck, shoulders
and gum during dental operations.
Axiostat – Mechanism of action
There are a number of Haemostatic wound dressing
technologies. Each technique has a unique agent and is available as
granular powder or impregnated on bandages. These techniques can be
classified as factor concentrators which use zeolite, muco-adhesive
agents such as Chitosan and procoagulant supplements such as Kaolin
agent.
Axio Clotting Technology uses Chitosan, that is
comprised of distributed β--linked D-glucosamine and
N-acetyl-D-glucosamine. Chitosan occurs naturally in shellfish and is
biocompatible. When positively-charged Chitosan comes to contact with
anions in the red blood cells, a very strong adhesive seal is formed
creating a mechanical barrier for the blood. Additionally, the
attraction causes platelet aggregation and activation creating the
formation of fibrin and eventually a blood clot. The formation of clot
occurs independently of natural clotting cascadeand therefore
patients with blood clotting disorders can also use it.
Chitosan is 100% natural and has inherent anti-bacterial, anti-fungal & haemostatic properties.
